The invention relates to a pharmaceutical formulation comprising 40-O-(2-hydroxy)ethyl-rapamycin in a high drug load part and an immediate release part. In addition, the invention relates to a formulation comprising 40-O-(2-hydroxy)ethyl-rapamycin in a first layer and a surfactant in a layer beneath the first layer. The pharmaceutical composition is particularly suitable for use as a medicament.本發明係關於一種醫藥調配物，其在高藥物負載部分及立即釋放部分中包含40-O-(2-羥基)乙基-雷帕黴素(rapamycin)。另外，本發明係關於一種調配物，其在第一層中包含40-O-(2-羥基)乙基-雷帕黴素及在該第一層下方之層中包含表面活性劑。該醫藥組合物尤其適宜用作藥劑。
