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Benzimidazole-based injection
专利权人:
ニプロ株式会社
发明人:
西山 要,城内 豊
申请号:
JP2009168587
公开号:
JP5691142B2
申请日:
2009.07.17
申请国别(地区):
JP
年份:
2015
代理人:
摘要:
Disclosed is a benzimidazole-based injection solution which does not cause hemolysis or local irritation when used as an injection solution. Specifically disclosed is a method for producing a benzimidazole-based injection solution, which comprises a step of preparing a benzimidazole-based solution by mixing a benzimidazole-based compound or a salt thereof and ammonia water in an aqueous solvent that contains no nonaqueous solvent, and a step of freeze-drying the solution. By this method, a benzimidazole-based injection solution which does not cause hemolysis or local irritation when used as an injection solution can be obtained. Since a benzimidazole-based compound or a salt thereof is sufficiently dissolved in an aqueous solvent that contains no nonaqueous solvent and is highly stable in the solvent, a high-quality benzimidazole-based injection solution can be obtained. In addition, the benzimidazole-based injection solution obtained by the method has excellent storage stability.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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