Lewis T. Williams,Hongbing Zhang,Yan Wang,Loriane Masuoka,Stephen Doberstein
申请号：
US11795915
公开号：
US08168588B2
申请日:
2006.01.25
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Pharmaceutical polypeptide compositions promote the survival of cardiac cells, recruit cardiac cells to the cardiac area, stimulate the differentiation of cardiac cells, stimulate the proliferation of cardiac cells, and promote the activity of cardiac cells, thereby treating cardiac conditions. Methods of providing these compositions to the cardiac area include catheterization and direct injection. In preferred embodiments, the compositions comprise one of more of the following growth factors: EGF, bFGF, cardiotrophin-1, thrombin, PDGF-BB, amphiregulin, epiregulin, HB-EGF, TGFalpha, betacellulin, heregulin alpha, NRG-1-beta1-HRG-beta1, FGF 9.
