CLAUDE SINGER,NEOMI GERSHON,ARINA CEAUSU,ANITA LIEBERMAN,JUDITH ARONHIME
申请号：
IN1259/MUMNP/2006
公开号：
IN254357B
申请日:
2006.10.26
申请国别(地区):
IN
年份:
2012
代理人:
摘要：
The present invention provides an improved process for preparing modafinil, whereby it may be isolated in high purity by a single crystallization. The process produces modafinil free of sulphone products of over-oxidation and other byproducts. The invention further provides new crystalline Forms II-VI of modafinil and processes for preparing them. Each of the new forms is differentiated by a unique powder X-ray diffraction pattern. The invention further provides pharmaceutical compositions containing novel modafinil Forms II-IV and VI.
