Universite Paris Descartes;Inserm Paris;Centre national de la recherche scientifique;Assistance Publique - Hopitaux de Paris
发明人:
Wolf, Jean-Philippe,Lombès, Anne,Bomsel, Morgane
申请号:
AU2016325378
公开号:
AU2016325378A1
申请日:
2016.09.21
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present invention relates to the use of a cyclic peptide comprising the tripeptide reproducing a binding site of fertilin beta to the oocyte integrin, for improving cellular energy metabolism. More particularly, the invention concerns the use of a cyclic peptide comprising the tripeptide FEEc for stimulating the energy metabolism of gametes or embryonic cells in the context of medically assisted procreation (MAP) protocols, in particular promoting the in vitro maturation of the oocyte, the fertilisation rate and the birth rate.