This creation provides a kind of needle set removal device, include a pedestal, an ontology and a fixture, the ontology, wherein one end detachably sets the what pedestal, and wherein the one end of the what ontology with respect to the what pedestal is arranged in one end to the fixture, the fixture defines a clamp space, the clamp space accommodates for the lid of a needle set and is clamped by the fixture, and thereby, the fixture of this creation can be fixed what pedestal for using, also it can remove from pedestal and be used with hand-held, so that user removes the syringe needle of needle set and needle is avoided to prick infection.本創作提供一種針具移除裝置,包含一底座、一本體與一夾具,該本體,其中一端可拆地設於該底座,該夾具其中一端設置於該本體相對於該底座的一端,該夾具定義一鉗夾空間,該鉗夾空間供一針具之蓋體容置而受該夾具夾持,藉此,本創作之夾具可被固定於底座供使用,亦可自底座拆下以手持使用,以便於使用者拆下針具的針頭而避免針扎感染。