Antibodies binding to EphB4 for inhibiting angiogenesis and tumor growth

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专利权人:

VASGENE THERAPEUTICS; INC.

发明人:

KRASNOPEROV, VALERY,ZOZULYA, SERGEY,KERTESZ, NATHALIE,REDDY, RAMACHANDRA,GILL, PARKASH

申请号：

NZ58411705

公开号：

NZ584117A

申请日:

2005.03.11

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Disclosed is an isolated antibody or antigen binding portion thereof that binds to an epitope situated within amino acids 324-429 or 430-537 of the extracellular portion of EphB4 and stimulates EphB4 kinase activity and promotes apoptosis in a tumor cell.

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