Ralph Steven Baric,Lisa Chon Lindesmith,Kari Moore Debbink,Eric Francis Donaldson,Jesica Anne Swanstrom
申请号:
US14213469
公开号:
US09975923B2
申请日:
2014.03.14
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides methods and compositions comprising a chimeric norovirus capsid protein comprising a norovirus VP1 major capsid protein backbone comprising a norovirus epitope selected from the group consisting of: a) Epitope A b) Epitope B c) Epitope C d) Epitope D e) Epitope E f) Epitope F and g) any combination of (a) through (f) above, wherein the norovirus epitope is from a norovirus strain that is different from the norovirus VP1 major capsid protein backbone.