FVIII peptidi in njihova uporaba pri toleriziranju hemofilikov

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专利权人:

APITOPE INTERNATIONAL NV

发明人:

WRAITH DAVID,WRAITH David

申请号：

SI200831186

公开号：

SI2227488T1

申请日:

2008.12.03

申请国别(地区):

SI

年份:

2014

代理人:

摘要：

The present invention provides a peptide comprising a core residue sequence derivable from human FVIII which peptide is capable of binding to an MHC class II molecule without further antigen processing. The present invention also relates to the use of such peptides for the prevention or suppression of inhibitor antibody formation in haemophilia A and/or acquired haemophilia.

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