The present disclosure relates to topical compositions comprising water, solvent, thickener, preservative and conditioning agent wherein the composition has a viscosity in the range 200-6000 cP at 25°C following exposure to gamma radiation. Also disclosed is the use of the said composition in a dressing and the use of compositions and dressings in treatment or prophylaxis of burns. The conditioning agent is a mineral complex derived from seawater. The solvent is preferably 1,3-propane diol. The thickener is preferably an acryloyldimethyl- taurate/VP crosspolymer and the preservative is preferably a mixture of phenoxyethanol, caprylyl glycol, chlorphenesin and a polyaminopropyl biguanide (PHMB). The composition maintains its integrity upon irradiation with gamma radiation, i.e., does not lose viscosity, colour or become denatured.
