An autoinjector comprising an outer housing in which can be mounted a syringe forholding a volume of medicament, the syringe for holding medicament having a needleat one end thereof, a syringe holder for supporting the syringe in an axial positionrelative to the outer housing, and an intermediate housing at least part of whichis located within said outer housing, characterised in that said intermediatehousing is provided with a blocking means capable of abutting the syringe or thesyringe holder so as to be capable of preventing forward axial movement of thesyringe when a forward axial force is applied to said needle before actuation ofthe autoinjector to deliver an injection, but incapable of preventing forward axialmovement of the syringe during actuation of the autoinjector to deliver an injection.