The present invention provides a pharmaceutical composition for skin wound healing, and specifically, the composition is a fermented soybean composition a fermented soybean fermentation solution prepared by co-cultivating a soybean liquid and more than one microbial probiotics group, wherein the microbial probiotics group is a group composed of microorganisms of the Bifidobacterium, Lactobacillus, Lactococcus lactis, and Streptococcus. Further, the soybean fermentation solution is undegreased soybean fermentation solution, and the soybean fermentation solution is added with an excipient to prepare a dosage form of liquid spray, gel, emulsion, cream and ointment. The soybean fermentation solution achieve the wound healing promoting effect by suppressing inflammation of the wound and increasing maturation of connective tissues and angiogenesis.本發明提供一種用於皮膚傷口癒合之醫藥組合物,具體而言該組合物為一大豆醱酵組合物,是以大豆液與一種以上的微生物益生菌群共同培養而製成的大豆醱酵液,其中該微生物益生菌群係由雙歧桿菌屬、乳桿菌屬、芽孢桿菌屬、乳酸球菌屬及鏈球菌屬之微生物所組成的群組。