Therapeutic methods and compositions involving allosteric kinase inhibition

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专利权人:

David A. Cheresh;Eric A. Murphy;Lee Daniel Arnold

发明人:

Eric A. Murphy,David A. Cheresh,Lee Daniel Arnold

申请号：

US13577431

公开号：

US09260417B2

申请日:

2011.02.07

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present invention is directed to methods and compositions for suppressing lymphangiogenesis, angiogenesis and/or tumor growth. The methods comprise contacting the tumor with a compound that (i) stabilizes a protein kinase in the inactive state and (ii) is not an ATP competitive inhibitor of the protein kinase in the active state.

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中国工程科技知识中心

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http://www.ckcest.cn/home/