This invention designs and builds multiple layers (two layers or more) of various dental devices, specifically denture base or denture, where printed multiple layered denture base with teeth cavities to receive artificial denture tooth materials to form final dental devices, such as partial and full dentures. It can also print denture teeth. This invention also designs and prints multiple layers (two layers or more) of denture base with artificial denture teeth to form final dental devices, such as partial and full dentures. A method for manufacturing a layered denture is provided. The invention provides a multiple layered denture base materials for printing a denture base. The invention also provides a multiple layered denture tooth materials for printing artificial denture teeth. Highly shape adjustable or shape memory polymer layer(s) may be used in these multiple layered denture base forms. Different layer of material has different mechanical and physical properties to meet different need, which provide added benefits to the patients, dental professional and dental laboratory.