Inhibitors of protein phosphatase 1, GADD34 and protein phosphatase 1/GADD34 complex, preparation and uses thereof

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专利权人:

Guido Kroemer

发明人:

Guido Kroemer,Laurence Zitvogel

申请号：

US12438833

公开号：

US08129340B2

申请日:

2007.09.07

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention relates to the use of a protein phosphatase inhibitor selected from an inhibitor of the catalytic subunit of the protein phosphatase 1 (PP1), an inhibitor of GADD34 and an inhibitor of the PP1/GADD34 complex to prepare a pharmaceutical composition to prevent or treat a cancer in a mammal, wherein the pharmaceutical composition is intended for administration in combination with a product used in a treatment of a cancer.

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