The present invention provides a use of Cardiospermum halicacabum extract in the manufacture of a composition for upregulating SOD2 expression, promoting skin repair and preventing skin damage by UV light. The Cardiospermum halicacabum extract significantly prevents skin damage by UV light.本發明提供一種風船葛萃取物用於製備提升SOD2基因表現、促進皮膚修復及預防皮膚受紫外光傷害之組合物的用途。該風船葛萃取物具有預防或治療紫外光對皮膚之傷害的功效。