GONZÁLEZ OJER, CARLOS,GOÑI ALLO, BEATRIZ,PASTOR FERNÁNDEZ, FIONA,YÁRNOZ DE MIGUEL, CAYETANA
申请号：
PL11770791
公开号：
PL2629756T3
申请日:
2011.10.19
申请国别(地区):
PL
年份:
2015
代理人:
摘要：
Anhydrous topical gel composition of mupirocin or its salts comprising: a) a lipophilic base selected from the group consisting of petrolatum, medium-chain triglycerides, isopropyl myristate and mixtures thereof； b) a bioadhesive selected from the group comprising polyvinylpyrrolidone and polymethacrylates； and c) a solvent selected from the group comprising ethanol, propanol, and isopropanol； which is stable and shows an increased residence time of the active ingredient in the skin, resulting in an improved clinical effect in the treatment of bacterial skin infections while maintaining the safety profile of the commercial pharmaceutical product.
