This application discloses liquid compositions for administration to a patient comprising midazolam and a pharmaceutically acceptable carrier, wherein the pH of the composition is about 6 or higher and / or an advantageous carrier system is present, the composition comprises less than about 200mg/ml cyclodextrin, and at least about 50% of the midazolam is present in solution. Uses of these compositions is also disclosed.本發明揭示一種投與給患者之包含咪達唑侖(midazolam)及醫藥上可接受載劑之液體組合物,其中該組合物之pH係約6或更高及/或存在有利的載劑系統,該組合物包含少於約200 mg/ml之環糊精,且溶液中存在至少約50%之咪達唑侖。亦揭示該等組合物之用途。