IgM Fc and J-chain mutations that affect IgM serum half-life
- 专利权人:
- IGM Biosciences; Inc.
- 发明人:
- BALIGA, Ramesh,KEYT, Bruce Alan,NG, Dean
- 申请号：
- AU2019227984
- 公开号：
- AU2019227984A1
- 申请日:
- 2019.03.01
- 申请国别(地区):
- AU
- 年份:
- 2020
- 代理人:
- 摘要：
- This disclosure provides an IgM antibody or IgM-like antibody comprising a variant J-chain and/or variant IgM heavy chain constant regions that can confer increased serum half-life upon the antibody.
- 来源网站：
- 中国工程科技知识中心
