CHEN JIANHE,LAU JESPER F,KODRA JA NOS TIBOR,WIECZOREK BIRGIT,LINDEROTH LARS,THA GERSEN HENNING,RASMUSSEN SALKA ELBA L,GARIBAY PATRICK WILLIAM
申请号：
IN201847029095
公开号：
IN201847029095A
申请日:
2018.08.02
申请国别(地区):
IN
年份:
2018
代理人:
摘要：
The invention relates to compounds derived from the EGF(A) domain of LDL-R in particular compounds comprising a peptide analogue of the wild-type EGF(A) (LDL-R(293- 332)) sequence and at least one substituent comprising at least one fatty acid group. The invention also relates to a pharmaceutical composition thereof and use a medicament. The novel EGF(A) compounds of the invention are useful as treatment e.g. in the field of cholesterol lowering dyslipidaemia and cardiovascular disease.
