Jorn Piel,Cristian Gurgui,Michael Francis Freeman,Agustinus Robert Uria,Maximilian Johannes Helf
申请号：
US14342539
公开号：
US20140234903A1
申请日:
2012.09.05
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A novel gene cluster encoding polypeptides involved in the generation of bio synthetically unique peptide-based compounds is described. In addition, new methods for biosynthetic engineering and production of modified peptides and proteins are disclosed. Furthermore, new tools for identification of homologue polypeptides and precursor peptides in other species are provided. In addition, peptide-based compounds and fusions of these compounds with functional moieties for treatment of disorders such as tumors are disclosed.
