Sitagliptin synthesis

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专利权人:

Generics [UK] Limited

发明人:

Gore, Vinayak Govind,Gadakar, Maheshkumar,Bhosle, Priyanka,Shinde, Suresh

申请号：

AU2010247193

公开号：

AU2010247193B2

申请日:

2010.05.10

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

The present invention relates to novel processes for the preparation of enantiomerically enriched β -amino acid derivatives such as β -amino esters useful for the synthesis of enantiomerically enriched biologically active molecules such as sitagliptin. The key step involves the resolution of the racemate with mandelic acid.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/