THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
发明人:
Kam W. LEONG,Wei LEONG,Bo PENG
申请号：
US16618281
公开号：
US20200171167A1
申请日:
2018.05.24
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention discloses cationic nucleic acid scavengers to effectively inhibit the activation of multiple nucleic acid sensing pattern recognition receptors (PRRs) to treat an inflammatory or immune response which is induced by a nucleic acid through the activation of the PRRs. The cationic nucleic acid scavengers include water soluble cationic polymers, cationic nanoparticles, and cationic micro-particles, and bind the nucleic acid in a manner that is independent of the sequences, structure or chemistry of the nucleic acid.
