COMBINATION THERAPY OF TUMOR TARGETED ICOS AGONISTS WITH T-CELL BISPECIFIC MOLECULES

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专利权人:

Hoffmann-La Roche Inc.

发明人:

Marina BACAC,Tanja FAUTI,Christian KLEIN,Johannes SAM,Pablo UMANA,Ramona MURR,Joerg ZIELONKA,Lucas HABEGGER

申请号：

US16903756

公开号：

US20200306373A1

申请日:

2020.06.17

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present invention relates to agonistic ICOS-binding molecules comprising at least one antigen binding domain that binds to a tumor-associated antigen and their use in combination with T-cell bispecific molecules in the treatment of cancer, the agonistic ICOS-binding molecules as such, pharmaceutical compositions comprising these molecules, and methods of using the same.

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中国工程科技知识中心

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http://www.ckcest.cn/home/