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Low molecular weight derivatives of carboxamide halogenated porphyrins, namely chlorins and bacteriochlorins, and their applications thereof
专利权人:
LUZITIN, S.A.;UNIVERSIDADE DE COIMBRA
发明人:
Goncalo Pereira Nascimento Costa,Nuno Paulo Ferreira Goncalves,Carlos Jorge Pereira Monteiro,Artur Carlos Reis De Abreu,Helder Tao Ferraz Cardoso Soares,Luis Gabriel Borges Rocha,Fabio Antonio Schaber
申请号:
US15570956
公开号:
US10450322B2
申请日:
2016.05.06
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to carboxamide halogenated porphyrin derivatives, in particular bacteriochlorin or chlorin, of formula (I) use of the same or a pharmaceutically acceptable salt thereof in photodynamic therapy, where the derivatives are able to detect and exhibit the presence of hyperproliferative disorders and, in the presence of an adequate lighting, to treat the same. The present invention also describes a pharmaceutical composition having the carboxamide halogenated porphyrin derivatives, in particular bacteria-chlorin or chlorin, of Formula (I) or a pharmaceutically acceptable salt thereof, for the treatment of cancer and/or microbial and/or viral infections, in humans or animals.
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