THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;INOVIO PHARMACEUTICALS, INC.;THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY
发明人:
WEINER, DAVID,MUTHUMANI, KARUPPIAH,YAN, JIAN
申请号：
CA3037486
公开号：
CA3037486A1
申请日:
2017.09.19
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Disclosed herein is a composition comprising a recombinant nucleic acid sequence that encodes an antibody to a Zika viral antigen, and functional fragments thereof. The invention also relates to a composition comprising the combination of a first composition that elicits an immune response in a mammal against zika virus and a second composition comprising a recombinant nucleic acid sequence encoding an antibody, a fragment thereof, a variant thereof, or a combination thereof. In some instances, the nucleic acid molecule comprises a nucleotide sequence encoding an anti-ZIKV -Envelope (anti-ZIKV E) Protein antibody.
