Wang, Yuzhuo,Choi, Stephen Yiu Chuen,Gleave, Martin E.,Xue, Hui,Collins, Colin C.,Gout, Peter Wilhelm
申请号：
AU2016363683
公开号：
AU2016363683A1
申请日:
2016.11.30
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
Provided herein are compositions, method and uses for modulating MCT4 activity or for the treatment of cancer. The compositions comprise antisense oligonucleotides (ASO) for administration to a cancer cell, wherein the cancer cell may be characterized by elevated expression of MCT4. The cancer may be selected from one or more of: prostate cancer renal cell carcinoma breast cancer cervical cancer liver cancer bladder cancer and small cell lung cancer pr. The prostate cancer may be castration-resistant prostate cancer (CRPC).
