Benign pigmented moles or athlete's foot or ringworm of the nails can betreated with locally applicable, especially topically formulated active ingredientsof formula (I) wherein X represents CO, CHOZ or CHNRZ, Z is selected from hydrogen,linear or branched (C-C) alkyl, linear or branched (C-C)alkenyl, linear or branched (C-C) alkynyl, (C-C)cycloalkyl, (C-C) aryl, (C-C)aralkyl, m- und p- represent CH(CH)COOM；COR； CSR； C (NR) R； SOR；SOOM； SONRR； SOO-artemisinyl； SONH-artemisinyl； PORR andPSRR； R represents a linear or branched (C-C)alkyl, a linear or branched (C-C) alkoxy； a linear or branched(C-C) alkenyl； a linear or branched (C-C)alkynyl； (C-C) cycloalkyl； (C-C)aryl； (C-C) aryloxy； (C-C)aralkyl； -(CH)-COOM, where n represents a whole numberbetween 1 and 6； or 10a-dihydroartemisinyl； R and R areindependently selected from linear or branched (C-C)alkyl； linear or branched (C-C) alkenyl； linear or branched(C-C) alkynyl； (C-C) cycloalkyl；(C-C) aryl； (C-C) aralkyl；OM； linear or branched (C-C) alkoxy； (C-C)aryloxy and NRR； R is selected from linearor branched (C-C) alkyl； linear or branched (C-C)alkenyl； linear or branched (C-C) alkynyl； (C-C)cycloalkyl； (C-C) aryl and (C-C)aralkyl； M represents hydrogen or a pharmaceutically acceptable cation； andR and R independnetly represent hydrogen or a linear orbranched (C-C) alkyl, or R and Rtogether form am alkylene bridge (C-C)； and R is selectedfrom hydrogen and the groups cited for R. Said compounds are also effectivein the prevention of acquired Naevus cell naevi.
