BAGUISI ALEXANDER B.,BEEUWKES REINIER,CASALE RALPH,KATES STEVEN A.,LADER ALAN S.
申请号:
NZ61037811
公开号:
NZ610378A
申请日:
2011.11.10
申请国别(地区):
NZ
年份:
2015
代理人:
摘要:
The disclosure relates to a family of compounds as shown in Formula (I), wherein X can either be absent of an amino acid and R and R’ are as disclosed in the specification. The disclosure also relates to a method of using these lipoyl compounds in the treatment of ischemic injury or ischemia-reperfusion injury. Examples of these compounds include: N-(R)-lipoyl-L-glutamyl-L-alanine N-(R)-lipoyl-3-aminobenzenesulfonic acid N-(R)-lipoyl-aminoethylphosponic acid N-(R)-lipoyliminodiacetic acid N-(R)-lipoyl-L-4-carboxyphenylalanine