The present invention discloses a percutaneously absorbable preparation, which comprises a drug storage layer, an adhesive layer and a support body, wherein the drug storage layer has a first main surface and a second main surface and contains a drug the adhesive layer is disposed on the first main surface of the drug storage layer, and contains polyorganosiloxane-containing silicone adhesives the support body is formed by covering the side surface of the drug storage layer and the second main surface, and the content of the silicone is 20 mass% or more of the total mass of the adhesive layer. The overall moisture permeability of the percutaneously absorbable preparation is 20 g/m2/24hr or more and 314 g/m2/24hr or less.本發明揭示一種經皮吸收製劑,其係包括藥物貯留層、黏著劑層及支持體者,上述藥物貯留層具有第1及第2主面,含有藥物;上述黏著劑層設置於上述藥物貯留層之上述第1主面側,含有包含聚有機矽氧烷之矽酮黏著劑;上述支持體以覆蓋上述藥物貯留層之側面及上述第2主面之方式形成;且上述矽酮黏著劑之含量相對於上述黏著劑層之總質量為20質量%以上,作為經皮吸收製劑整體之透濕度為20 g/m2・24 hr以上且314 g/m2・24 hr以下。無