Immunity and the inflammation Characteristic disease and manner and the constituent which remedy fault are disclosed. Manner and the constituent of specification the medicine which inhibits S1P lyase activity and at least one further immunity restrainer and/or include the dosage of the anti- inflammation medicine.< Choice figure >It is not免疫性及び炎症性の疾患及び障害を治療する方法及び組成物を開示する。特定の方法及び組成物は、S1Pリアーゼ活性を阻害する薬剤並びに少なくとも1つのさらなる免疫抑制剤及び/又は抗炎症剤の投与を含む。【選択図】なし