Michael T. McMahon,Kannie Wai-Yan Chan,Michael Christopher Giano,Nikita Oskolkov,Joel Patrick Schneider,Xiaolei Song
申请号:
US14787039
公开号:
US20160106871A1
申请日:
2014.04.28
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention provides novel hydrogels through peptides, which are designed to self-assemble and produce magnetic resonance (MR) contrast through chemical exchange saturation transfer (CEST). The location and integrity of these gels could consequently be tracked using MR imaging. The self-assembly of the peptides into hydrogels can be brought about by a change in pH, ionic strength, temperature, and concentration of ions.