TECHNIQUE POUR L'ISOLEMENT/LA CULTURE DE CELLULE SOUCHE ÉPITHÉLIALE COLORECTALE, ET TECHNIQUE POUR LA TRANSPLANTATION D'ÉPITHÉLIUM COLORECTAL À L'AIDE DE LADITE TECHNIQUE
National University Corporation Tokyo Medical and Dental University
发明人:
申请号:
EP12844458.5
公开号:
EP2772534A1
申请日:
2012.10.26
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
It is an object of the present invention to provide a culture medium for in vitro culture of a colorectal epithelial stem cell or the like, a method of in vitro culturing a colorectal epithelial stem cell or the like using the culture medium, a prophylactic or therapeutic agent for a bowel disease containing a colorectal epithelial stem cell or the like cultured by the method, a method of administrating, i.e., transplanting a colorectal epithelial stem cell or the like cultured by the method to a bowel disease patient, and a method of isolating a colorectal epithelial stem cell or the like. The culture medium for in vitro culture of a colorectal epithelial stem cell and/or a colorectal epithelial cell characteristically contains serum albumin, Wnt3a, and r-spondin-1.