INIBIZIONE DELLA GENERAZIONE DI ROS IPOSSIA DIPENDENTE PER DIMINUIRE LA RESISTENZA AI FARMACI ANTITUMORALI, RADIORESISTENZA E FORMAZIONE DELLE CANCER STEM CELL E FENOTIPO METASTATICO
The present invention relates to the use of systems involved in ROS generation (reactive oxygen species) to reduce resistance to chemotherapy and radiation therapy, reduce cancer stem cell formation and inhibit the metastatic phenotype the subject matter of the invention further relates to inhibitors of ROS generation serving to reduce resistance to chemotherapy and radiation therapy and inhibit cancer stem cell formation and inhibit the metastatic phenotype.