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Compositions for the treatment of diseases
专利权人:
AMPIO PHARMACEUTICALS INC
发明人:
BAR-OR DAVID
申请号:
NZ60760011
公开号:
NZ607600A
申请日:
2011.09.07
申请国别(地区):
NZ
年份:
2015
代理人:
摘要:
The disclosure relates to a method of inhibiting vascular hyperpermeability in an animal in need thereof. The method comprises administering an effective amount of a diketopiperazme, a prodrug of a diketopiperazme or a pharmaceutically-acceptable salt of either of them to the animal, wherein the diketopiperazme has the formula set forth in the specification. The disclosure also relates to a method of modulating the cytoskeleton of an endothelial cell in an animal. The method comprises administering an effective amount of a diketopiperazme, a prodrug of a diketopiperazme or a pharmaceutically-acceptable salt of either of them to the animal, wherein the diketopiperazme has the formula set forth in the specification. The disclosure further relates to a kit. The kit comprises a diketopiperazme, a prodrug of a diketopiperazme or a pharmaceutically-acceptable salt of either of them to the animal, wherein the diketopiperazme has the formula set forth in the specification.
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