AGENTS, USES AND METHODS

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专利权人:

H. Lundbeck A/S

发明人:

Pekka Kallunki,Karina Fog

申请号：

US16469482

公开号：

US20200024337A1

申请日:

2017.12.14

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present invention relates to a mouse antibody denoted m2E6, chimeric ch2E6, as well as to 3 humanized forms (2E6-HLD1, 2E6-HLD2 and 2E6-HLD3) and affinity matured forms of HLD1: 7A10, 5A1, 9D7, 9G11, 7C4, L3, 8D9, 9C12 or 6B6 to create higher affinity antibodies.

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