This invention relates to pharmaceutical compositions consisting of a semisynthetic derivative of vinca alkaloid, stable at room temperature, in which said derivative is present in the form of a freeze-dried product obtained in the presence of at least one carbohydrate.本發明係有關由室溫下安定之長春花生物鹼之半合成衍生物所組成之藥學組成物,其中該衍生物係呈於至少一種碳水化合物存在下獲得之凍乾產物形式存在。