Rachel Marie PUGH;Philip Alexander MACFAUL;Ian Alun NASH;Armelle Marie-Laudine JANIN;Emily Jane ROBERTS
发明人:
Armelle Marie-Laudine JANIN,Philip Alexander MACFAUL,Rachel Marie PUGH,Emily Jane ROBERTS,Ian Alun NASH
申请号：
US13185981
公开号：
US20120022110A1
申请日:
2011.07.19
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A pharmaceutical depot comprising (i) 5-fluoro-2-[[(1S)-1-(5-fluoro-2-pyridyl)ethyl]amino]-6-[(5-isopropoxy-1H-pyrazol-3-yl)amino]pyridine-3-carbonitrile, or a pharmaceutically-acceptable salt thereof, as a pharmaceutical agent (PA) and (ii) a polymer which degrades to create an acidic microclimate, wherein the PA is released from the polymer upon polymer degradation.
