A tablet splitting apparatus (20, 20A, 20B) includes a housing (24) in which a guide (31, 31A), a catcher (34), and a splitting mechanism (40, 40A, 40B) are accommodated. The housing (24) includes an opening and a support (28, 28A, 28B). The support (28, 28A, 28B) and the guide (31, 31A) each include a sliding portion. The guide (31, 31A) disposed at the supporting position is slid along the sliding portion so as to be detachable from the supporting position. The blades (41, 42) and the blade shifters (43, 44) each include a sliding portion and are in a slidable contact with each other at the sliding portions while the blades (41, 42) are attached to the respective predetermined positions. The blades (41, 42) attached to the blade shifters (43, 44) are slid along the sliding portions so as to be detachable from the blade shifters (43, 44).
