Compositions and methods for stabilizing liposomal camptothecin formulations

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专利权人:

Tekmira Pharmaceuticals Corporation

发明人:

Hope, Michael J.,Mui, Barbara,Madden, Thomas D.

申请号：

AU2005304914

公开号：

AU2005304914B2

申请日:

2005.11.04

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

The present invention is directed to liposomal compositions comprising a camptothecin, which are optimized to reduce camptothecin degradation and/or precipitation of camptothecin degradation products in the external medium. The invention further provides improved methods of formulating liposomal camptothecins, kits comprising liposome-encapsulated camptothecins, and methods of using the same to treat a variety of diseases and disorders, including cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/