A peptidic hydrolyzate enriched in bioactive peptide, capable of reinforcing the skin barrier function and stimulating epidermal differentiation is described. Additionally, a cosmetic and/or pharmaceutical composition that includes a physiologically acceptable medium and the peptidic hydrolyzate as active principle are described. The cosmetic composition activates the HMG-CoA reductase in the cutaneous cells and treats the cutaneous signs of aging and photo-aging.