SOMAR Corp.;KOREAN RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
发明人:
Bong Hyun Chung,Hirohiko Ise,Toshihiro Akaike,Sun-Jung Kim
申请号:
US14287943
公开号:
US09617543B2
申请日:
2014.05.27
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A sugar chain-containing polymer that enables targeting to the lesion area of liver fibrosis and is useful for imaging, diagnosis and therapy of liver fibrosis; and a sugar chain-containing polymer complex comprising the polymer as a carrier for an anionic substance useful fix therapy and the like; are provided. The polymer is a sugar chain-containing polymer which is a cationic polymer comprising an amine, which polymer comprises N-acetylglucosamine bound thereto. The polymer preferably has a disulfide bond. The polymer preferably has a structure in which polyethyleneimine is linked via a disulfide bond.