Tissue fixation systems and tissue manipulators are described herein. In addition, methods of using a tissue fixation system and a tissue manipulator, methods of manufacturing a tissue manipulator, and kits that include a tissue fixation system and a tissue manipulator are described herein. An example embodiment of a tissue fixation system includes a mounting plate, a mounting jaw releasably attached to the mounting plate, a mounting clamp releasably attached to the mounting plate, and a plurality of fasteners.