The Regents of The University of Michigan;密執安大學評議會
发明人:
WHITEHEAD, Christopher Emil,LEOPOLD, Judith S.
申请号:
HK18105274
公开号:
HK1248520A1
申请日:
2018.04.23
申请国别(地区):
HK
年份:
2018
代理人:
摘要:
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazoline structure or a quinoline structure which function as dual inhibitors of EGFR proteins and PI3K proteins, and their use as therapeutics for the treatment of cancer and other diseases.