Embodiments of the present disclosure provide for nanoparticles for acoustic imaging, methods of using the nanoparticles, methods of imaging a condition, and the like. Embodiments of the present disclosure include nanoparticles (e.g., silica nanoparticles) that can be used to image, detect, study, monitor, evaluate, and/or screen a sample or subject (e.g., whole-body or a portion thereof).
