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IMMUNISATION PASSIVE ANTI-GLUCOSAMINIDASE POUR LES INFECTIONS PAR STAPHYLOCOCCUS AUREUS
专利权人:
UNIVERSITY OF ROCHESTER
发明人:
SCHWARZ, EDWARD M.,SULLIVAN, MARK A.,DAISS, JOHN L.
申请号:
CA2797121
公开号:
CA2797121C
申请日:
2011.05.03
申请国别(地区):
CA
年份:
2020
代理人:
摘要:
The present invention is directed to a monoclonal antibody that bindsspecifically to a Staphylococcus aureus glucosaminidaseand inhibits in vivo growth of S. aureus. Also disclosed are monoclonalantibody binding portions, recombinant orhybridoma cell lines, pharmaceutical compositions containing the monoclonalantibody or binding portions thereof, and methodsof treating 5*. aureus infection and osteomyelitis, and methods forintroducing an orthopedic implant into a patient using the monoclonalantibody, binding portion, or pharmaceutical composition of the presentinvention.
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