An object of the present invention is to provide a drug preparing system and a drug preparing device both capable of simplifying management of prescription data. A drug preparing system (1) includes: a host computer (10) that creates one piece of prescription data regarding a plurality of patients belong to a same group; a computer (20) that obtains the prescription data created by the host computer and that creates drug preparation data based on the prescription data; and a packaging machine (100) that prepares a drug based on the drug preparation data created by the computer.