MÉTHODES ET COMPOSITIONS D'INHIBITION DE L'INTERACTION DE LA MÉNINE AVEC LES PROTÉINES MLL

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专利权人:

Inc.;The Regents of The University of Michigan;Kura Oncology, Inc.;Kura Oncology

发明人:

GREMBECKA, Jolanta,BORKIN, Dmitry,CIERPICKI, Tomasz,POLLOCK, Jonathan,LI, Liansheng,WU, Tao,FENG, Jun,REN, Pingda,LIU, Yi,KLOSSOWSKI, Szymon

申请号：

EP16803881

公开号：

EP3303317A4

申请日:

2016.03.16

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present disclosure provides compositions and methods of use to inhibit the interaction of menin with MLL1, MLL2 and MLL-fusion oncoproteins. The compositions and methods of use are useful for the treatment of leukemia, solid cancers, diabetes and other diseases dependent on activity of MLL1, MLL2, MLL fusion proteins, and/or menin.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/