Highly concentrated solutions are disclosed along with methods of inhibitingand/orameliorating functional neurological disorders of the brain. The methodmay include administering directly to a brain of a subject a medicamentmultiple timesover a time period of at least two days. The medicament may include a half-life ofless than 2 hour in the cerebrospinal fluid The method may include inhibitingand/orameliorating a functional neurological disorder of the brain using themedicant.