MORTON, JOSH,BRATCHER, BARRY,SWOPE, KELSI,HIATT, EMMETT ERNEST, III,HUME, STEVEN D.,ZEITLIN, LARRY
申请号:
CA2971151
公开号:
CA2971151A1
申请日:
2014.10.03
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
A new platform method to purify plant-based monoclonal antibodies is provided. Such a method includes an antibody purification platform that involves a standardized procedure for the production of a wide array of different antibodies within a simplified context. The versatility of the overall purification process accords a one-size-fits-all approach for myriad antibody products and includes plant tissue harvesting, extraction and clarification, filtrate generation, a succession of column chromatography procedures, and buffer exposure to provide the desired monoclonal antibodies in proper filtered and purified form for further incorporation and/or use within medicaments and other formulations. Thus, the purified monoclonal antibodies produced thereby such a method are also encompassed within this invention.